In The real world test after test, the M1 Macs are not merely inching past

4 min readDec 3, 2020

They found the most viral RNA in the olfactory mucosa, the lining at the top of the nasal cavity. In part because of its close proximity to the brain, the researchers think the olfactory mucosa is the most likely “port of entry” into the central nervous system. Some brain cells project into the olfactory mucosa, and these may act like highways for the virus to travel further into the brain, once it has crossed over from the nose.

This is early research, partially limited by a small sample size, and partially by the tricky nature of doing autopsy research during a global pandemic. Infected cells may die in the variable time between a person’s death and the moment a scientist can examine their body, which no doubt complicate any effort to trace the path the virus travels. “One caveat to note with the Covid-19 cases reported here,” the authors write, “is the relatively long postmortem interval, an almost insurmountable obstacle in autopsy studies, especially when performed under the emergency-like conditions encountered during a pandemic situation.”

Usually, we organize related Notebooks together in a folder. In order to access them, we need to go through the directory structure in the File Browser, which is cumbersome.Distribution-based Clustering: This clustering algorithm assumes the data is composed of probability distributions and then clusters the data into various versions of that distribution.Clustering algorithms are a group of unsupervised algorithms used to group data points. Points within the same cluster are more similar to each other than to points in different clusters.

Research published Monday in the journal Nature Neuroscience sheds light on how SARS-CoV-2 may do so. A team led by Helena Radbruch, PhD, and Frank L. Heppner, PhD, of the Charité–Universitätsmedizin Berlin examined the bodies of 33 people who had died of Covid-19 and concluded that the virus likely entered the brain through the nose.

When I first started out, we had an idea, turned it into a UI, and hired developers to make it real. After nearly a year and tens of thousands of dollars — we launched it.

If you are one of those people, you have come to the right place. Here I plan to break it down into digestible pieces exactly what it is that Apple has done with the M1. Specifically the questions I think a lot of people have are:

0*9dAlouEyy4mqe7jFCentroid-based Clustering: This clustering algorithm organizes the data into clusters based on initial conditions and outliers. k-means is the most knowledgeable and used centroid-based clustering algorithm.But the default way most of us talk to customers and prospects is unscientific and fraught with confirmation bias, putting us in danger of being lied to and wasting months building something nobody wants.They detected viral RNA in the brain and the nasopharynx, the upper region of the throat that connects to the nasal cavity (and is also where viral infection and replication is first thought to take place). Bordered on the bottom by the roof of the mouth and on the top by the space that holds the brain, the nasal cavity is the mound-shaped enclosure that makes the inside of the nose.I learned this truth the hard way over the past decade founding multiple companies — but it wasn’t until I was working on my third startup that I came to understand a better way to actually understand users.
In their hunt for the presence of the coronavirus in the nose and brain, the researchers also detected it in the cerebellum — a part of the brain that is not directly connected to the olfactory mucosa. This suggests that there are other, nonnasal roads leading to the brain. (One possibility is that it rides across the blood-brain barrier in white blood cells; another is that it gets in through the central nervous system’s endothelium.) They also detected low levels of the coronavirus in parts of the eyes and oral mucosa, suggesting that the virus may also be able to enter the central nervous system through these routes.
Sure you could try to Google this, but if you try to learn what Apple has done beyond the superficial explanations, you will quickly get buried in highly technical jargon such as M1 using very wide instruction decoders, enormous re-order buffer (ROB) etc. Unless you are a CPU hardware geek, a lot of this will simply be gobbledegook.

In The real world test after test, the M1 Macs are not merely inching past

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